estrogen receptor antagonist 1 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T63582	Estrogen receptor antagonist 1
	Estrogen receptor antagonist 1 is a potent antagonist of the estrogen receptor. Estrogen receptor antagonist 1 has shown research potential in breast cancer disease.
T11236	Giredestrant tartrate	Estrogen receptor antagonist 1	Estrogen Receptor/ERR , Others
	Giredestrant tartrate (Estrogen receptor antagonist 1) is a novel, orally active, selective and effective non-steroidal estrogen receptor antagonist. Giredestrant tartrate strongly binds to ER, resulting in the failure o...		Estrogen Receptor/ERR , Others
T62764	Estrogen receptor α antagonist 1
	Estrogen receptor α antagonist 1 (compound 35) is a highly selective estrogen receptor α antagonist that acts on estrogen receptor α (IC50: 0.02 μM), estrogen receptor β (IC50. Estrogen receptor α antagonist 1 (compound ...
T11237	Camizestrant	Estrogen receptor antagonist 2	Estrogen Receptor/ERR
	Camizestrant (Estrogen receptor antagonist 2) is an antagonist of the estrogen receptor and can be used in studies about ER+ HER2-advanced breast cancer[1].		Estrogen Receptor/ERR
T15191	PROTAC ERRα ligand 1		Estrogen Receptor/ERR , Estrogen/progestogen Receptor
	PROTAC ERRα ligand 1 is an α (ERRα) antagonist of estrogen-related receptor (IC50s of 0.04 and 2.8 μM for ERRα and ERRγ, respectively).		Estrogen Receptor/ERR , Estrogen/progestogen Receptor
T20625	Prochloraz	Sporgon,Prelude	Estrogen Receptor/ERR , AhR , Androgen Receptor , Antifungal
	Prochloraz (Prelude) is a broad-spectrum contact imidazole fungicide. Prochloraz inhibits human placental microsomal aromatase in vitro (IC50 = 40 nM). Prochloraz also acts as an estrogen receptor (IC50s = 25 μM) and and...
T11230	ERRα antagonist-1	ERR+/- antagonist-1,ERRa antagonist-1	Estrogen/progestogen Receptor
	ERRα antagonist-1 (ERR+/- antagonist-1) is a high-affinity, selective antagonist of the estrogen-related receptor α (ERRα). It effectively prevents the interaction of ERRα with both Proliferator-activated Receptor γ Coac...		Estrogen/progestogen Receptor
T60115	EM-651	2H-1-Benzopyran-7-ol, 3-(4-hydroxyphenyl)-4-methyl-2-[4-[2-(1-piperidinyl)ethoxy]phenyl]-, (2R)-
	EM-651 (2H-1-Benzopyran-7-ol, 3-(4-hydroxyphenyl)-4-methyl-2-[4-[2-(1-piperidinyl)ethoxy]phenyl]-, (2R)-) is an enantiomer of EM-652, IC50=20.0 nM. EM-652 is an orally active pure antiestrogen and selective estrogen rece...
T61909	Estrogen receptor antagonist 7
	Estrogen Receptor Antagonist 7 (Compound 13) is a potent antagonist of estrogen receptors (ER), demonstrating antiproliferative effects against breast and ovarian cancer cells, along with anticancer and anti-uterotrophic...
T63106	Estrogen receptor antagonist 4
	Estrogen Receptor Antagonist 4 is a potent inhibitor of the estrogen receptor (ER), crucial for regulating cell growth, differentiation, and apoptosis. This compound holds promise for cancer research[1].
T64026	ERα antagonist 1
	ERα antagonist 1 is a selective, potent, covalent estrogen receptor alpha (ERα) antagonist that blocks the cell cycle of MCF-7 cells in G0/G1 phase and induces apoptosis.
T82439	Estrogen receptor modulator 10		Estrogen Receptor/ERR
	Compound G-5b, an estrogen receptor modulator 10, functions as an estrogen receptor (ER) antagonist (IC50=6.7 nM) and degrader (DC50=0.4 nM). It has the capability to induce apoptosis and block cells at the G1/G0 phase, ...		Estrogen Receptor/ERR
T35667	Napyradiomycin A1	Napyradiomycin A1
	Napyradiomycin A1is a fungal metabolite originally isolated fromC. rubraand has diverse biological activities.1,2It is active againstS. aureus,M. luteus,B. anthracis,C. bovis, andM. smegmatis(MICs = 1.56-12.5 μg/ml).1Nap...
T76566	Fsh receptor-binding inhibitor fragment(bi-10)
	FSH receptor-binding inhibitor fragment (bi-10) is a potent antagonist that inhibits the binding of follicle-stimulating hormone (FSH) to its receptor (FSHR), modifying FSH activity at the receptor level. It suppresses o...